Crystal Structure of human cyclic GMP-AMP synthase in complex with 6-(4-chlorophenyl)-10,11-dimethoxy-7-methyl-2,4,6-triazatricyclo[7.3.1.05,13]trideca-1(12),2,4,7,9(13),10-hexaene

Protein Data Bank Japan2026-02-18 更新2026-03-21 收录

下载链接：

https://pdbj.org/mine/summary/7ftp

下载链接

链接失效反馈

官方服务：

资源简介：

Crystal Structure of human cyclic GMP-AMP synthase in complex with 6-(4-chlorophenyl)-10,11-dimethoxy-7-methyl-2,4,6-triazatricyclo[7.3.1.05,13]trideca-1(12),2,4,7,9(13),10-hexaene Descriptor: 4-(4-chlorophenyl)-7,8-dimethoxy-5-methyl-4H-pyrido[2,3,4-de]quinazoline, Cyclic GMP-AMP synthase, ZINC ION Authors: Leibrock, L, Benz, J, Groebke-Zbinden, K, Zhang, Z, Rudolph, M.G. Deposit date: 2023-02-08 Release date: 2024-02-21 Last modified: 2026-02-18 Method: X-RAY DIFFRACTION (2.48 Å) Cite: Crystal Structure of a human cyclic GMP-AMP synthase complex To be published

人类环状GMP-AMP合酶（cyclic GMP-AMP synthase）与6-(4-氯苯基)-10,11-二甲氧基-7-甲基-2,4,6-三氮杂三环[7.3.1.05,13]十三碳-1(12),2,4,7,9(13),10-六烯复合物的晶体结构配体描述：4-(4-氯苯基)-7,8-二甲氧基-5-甲基-4H-吡啶并[2,3,4-de]喹唑啉、环状GMP-AMP合酶、锌离子作者：Leibrock, L、Benz, J、Groebke-Zbinden, K、Zhang, Z、Rudolph, M.G. 沉积日期：2023-02-08 发布日期：2024-02-21 最后修改日期：2026-02-18 实验方法：X射线衍射（X-RAY DIFFRACTION），分辨率2.48埃引用文献：人类环状GMP-AMP合酶复合物的晶体结构，待发表

创建时间：

2023-02-08