Altered Frequency and Phenotype of HLA-G-Expressing DC-10 in Type 1 Diabetes Patients at Onset and in Subjects at Risk to Develop the Disease.

In the manuscript "Altered Frequency and Phenotype of HLA-G-Expressing DC-10 in Type 1 Diabetes Patients at Onset and in Subjects at Risk to Develop the Disease" (doi: 10.3389/fimmu.2021.750162.), we reported, for the first time, the evaluation of a population of HLA-G-expressing tolerogenic dendritic cells in the peripheral blood of T1D patients and first-degree relatives demonstrating the impairment in the number and phenotype of DC-10 is associated with the risk to T1D.
The three dataset here loaded (Raw_data_1, 2, and 3) contain all the clinical and immunological data, supporting our conclusions, that have been used to build the manuscript.
An additional file (raw_data_description) contains the main guidelines to correctly associate the raw data with the corresponding figure/table in the manuscript.

在《新发1型糖尿病（Type 1 Diabetes, T1D）患者及疾病易感人群中表达人类白细胞抗原G（HLA-G）的DC-10细胞的频率与表型异常》（DOI: 10.3389/fimmu.2021.750162）的研究手稿中，我们首次报道了对1型糖尿病患者及一级亲属外周血中表达HLA-G的致耐受树突状细胞群体的评估，结果显示DC-10细胞的数量与表型异常与T1D发病风险相关。本次上传的三份数据集（Raw_data_1、Raw_data_2与Raw_data_3）包含了支撑本研究结论的全部临床与免疫学数据，所有数据均用于该手稿的撰写。另有补充文件raw_data_description，载明了将原始数据与手稿中对应图表正确关联的主要指南。