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Crystal structure of ternary complex Helios-ZF2:I-19:CRBN:DDB1

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Protein Data Bank Japan2025-10-22 更新2026-08-24 收录
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Crystal structure of ternary complex Helios-ZF2:I-19:CRBN:DDB1 Descriptor: (3S)-3-[5-(1-benzyl-4-hydroxypiperidin-4-yl)-1-oxo-1,3-dihydro-2H-isoindol-2-yl]piperidine-2,6-dione, DNA damage-binding protein 1, Protein cereblon, ... Authors: Zhu, J, Pagarigan, B.E, Tran, E.T. Deposit date: 2025-08-14 Release date: 2025-10-01 Last modified: 2025-10-22 Method: X-RAY DIFFRACTION (3.406 Å) Cite: Application of Weighted Interaction-Fingerprints for Rationalizing Neosubstrate Potency and Selectivity of Cereblon-Based Molecular Glues. J.Med.Chem., 68, 2025

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2025-08-14
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