Transcriptome analysis of Glomerella cingulata cultured in bifemetstrobin-amended PDB medium.

Tea (Camellia sinensis) is among the most widely consumed non alcoholic beverages and a major cash crop in many tropical and subtropical regions. Its yield and quality are frequently constrained by fungal diseases, among which anthracnose, caused by Glomerella cingulata, is particularly destructive in the field and during post harvest handling. Epidemics lead to defoliation, necrotic lesions, and quality losses through alterations in key biochemical constituents that underpin flavor and health attributes, ultimately reducing market value . Outbreaks of tea anthracnose have been reported across multiple tea growing provinces in China and other producing regions. Although chemical control remains central to management, increasing pressure for residue compliance, environmental stewardship, and resistance risk mitigation necessitates the development of new antifungal agents with clarified modes of action (MoA) to guide rational use. By analyzing the transcriptome of G. cingulata cultured in a PDB medium supplemented with bifemetstrobin, it helps us understand the pathogenesis of G. cingulata and further prevent and control cucumber target disease caused by this pathogen in the field.

茶树（Camellia sinensis）是全球范围内消费最广泛的非酒精饮品之一，同时也是诸多热带、亚热带地区的重要经济作物。其产量与品质常受真菌病害制约，其中由胶孢炭疽菌（Glomerella cingulata）引发的炭疽病，在田间种植与采后储运环节均具有极强破坏性。该病害流行可导致茶树落叶、产生坏死病斑，并通过改变支撑风味与健康品质的关键生化成分引发品质损失，最终降低市场价值。中国多个茶叶种植省份及其他产茶区域均有茶树炭疽病暴发的相关报道。尽管化学防治仍是当前病害防控的核心手段，但随着农药残留合规、环境保护以及抗性风险防控的压力日益增大，亟需开发作用模式（Mode of Action, MoA）明确的新型抗真菌药剂，以指导科学合理用药。通过对添加了bifemetstrobin的马铃薯葡萄糖肉汤（Potato Dextrose Broth, PDB）培养基中培养的胶孢炭疽菌转录组进行分析，可助力我们解析该病原菌的致病机制，进而进一步防控田间由该致病菌引发的黄瓜靶斑病。