GLIM phenotypic and etiological criteria.

IntroductionOlder individuals are at risk of malnutrition resulting from chronic diseases-related body and muscle mass reduction. In turn, nutritional deficiencies may enhance catabolic processes, leading to accelerated aging and comorbidity, thus creating a vicious cycle. Our study aimed to assess the prevalence of malnutrition using the Global Leadership Initiative on Malnutrition (GLIM) criteria and to determine the health correlates of malnutrition in a representative sample of community-dwelling older adults.MethodsWe used the GLIM criteria to diagnose malnutrition in 5,614 participants of the PolSenior2 study. The PolSenior2 study was a population-based survey designed to assess the medical, psychological, social, and economic characteristics of community-dwelling older adults.ResultsMalnutrition was diagnosed in 13.4% of the participants using the GLIM criteria. Results of multiple logistic regression showed that the risk of depression [OR 4.18, pConclusionDue to the high risk of malnutrition, special attention should be paid to individuals in late old age. Suspected malnutrition should also be considered in people at risk of depression, with peptic ulcer disease, past stroke, and cognitive impairment. Chronic pain should also prompt the diagnosis for malnutrition.引言：老年人群易因慢性病导致体质量与肌肉量减少，进而面临营养不良风险。反之，营养不足可加剧分解代谢过程，加速衰老并增加共病发生风险，最终形成恶性循环。本研究旨在采用营养不良全球领导力倡议（Global Leadership Initiative on Malnutrition, GLIM）标准，评估社区居住老年人群的营养不良患病率，并在具有代表性的社区老年人群样本中明确营养不良的健康相关关联因素。 研究方法：本研究纳入PolSenior2研究的5614名参与者，采用GLIM标准开展营养不良诊断。PolSenior2研究为一项基于人群的流行病学调查，旨在评估社区居住老年人群的医学、心理、社会及经济特征。 研究结果：依据GLIM标准，13.4%的参与者被确诊为营养不良。多因素logistic回归分析结果显示，抑郁相关风险[比值比（Odds Ratio, OR）=4.18，P 研究结论：鉴于营养不良的高发病风险，临床与公共卫生工作中应特别关注高龄老年人群。对于存在抑郁风险、合并消化性溃疡病史、既往脑卒中及认知功能损害的人群，也应将可疑营养不良纳入鉴别诊断范畴。慢性疼痛同样应作为营养不良诊断的重要提示指征。