Global analysis of genes differentially expressed in branching and non-branching regions of the mouse embryonic lung. Mus musculus

During development, the proximal and distal regions of respiratory tract undergo distinct processes that ultimately give rise to conducting airways and alveoli. To gain insights into the genetic pathways differentially activated in these regions when branching morphogenesis is initiating, we characterized their transcriptional profiles in murine rudiments isolated at embryonic day 11.5. Keywords: parallel sample

在机体发育进程中，呼吸道的近端与远端区域会经历各自独特的发育程序，最终分别分化形成传导气道与肺泡。为深入解析分支形态发生（branching morphogenesis）启动阶段时，这两个区域内差异激活的遗传通路，我们对胚胎第11.5天分离得到的小鼠呼吸道原基的转录谱（transcriptional profiles）开展了系统表征分析。关键词：平行样本