five

FC-3P

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NIAID Data Ecosystem2026-05-02 收录
下载链接:
https://figshare.com/articles/dataset/FC-3P/25810699
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资源简介:
FC-3P investigates the impact of Lactobacillus paracasei treatment on the gut microbiota in Clostridioides difficile infection. Fecal samples from mice post-infection were processed using Invitrogen with sequencing on the Ion Torrent NGS System. Analysis via Ion Reporter SW (16S) revealed shifts in microbial taxa dynamics over days 1, 3, and 6, shedding light on the potential of probiotics in modulating gut microbiota during C. difficile infection. The identification of the sample FC-3P: F: Denotes the strain ST-42 of Clostridioides difficile. C: Represents timepoint 2, indicating sampling after C. difficile infection. 3: Refers to the specific mouse number under investigation. P: Indicates the treatment administered, which in this case is Lactobacillus paracasei.

FC-3P数据集研究了副干酪乳杆菌(Lactobacillus paracasei)干预对艰难梭菌(Clostridioides difficile)感染小鼠肠道菌群的影响。研究人员收集了感染后小鼠的粪便样本,采用Invitrogen的实验流程完成样本处理,并在离子激流(Ion Torrent)新一代测序(NGS)系统上完成测序。通过Ion Reporter SW(16S)开展数据分析后,观测到感染后第1、3、6天微生物类群的动态变化,为阐明益生菌在艰难梭菌感染期间调控肠道菌群的潜在作用提供了科学依据。 样本FC-3P的命名规则如下: F:代表艰难梭菌菌株ST-42; C:代表时间点2,即艰难梭菌感染后的样本采集节点; 3:指代本次研究的特定小鼠编号; P:表示施加的干预措施,本研究中为副干酪乳杆菌处理。
创建时间:
2024-06-19
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