OPTIMIZING SIGNAL DETECTION PERFORMANCE IN PHARMACOVIGILENCE: INSIGHTS FROM A VIGIGRADE ANALYSIS

Cleaned and deduplicated FAERS ADR reports (2014 - 2023) for immune checkpint inhibitors, processed from quaterly ASCII files using SAS® 9.4. Data were sorted, merged and standerdised using primaryid and caseid, with MedDRA v27.0 applied where relevant.本数据集为2014至2023年期间针对免疫检查点抑制剂（immune checkpoint inhibitors）的、经清洗与去重处理的美国食品药品监督管理局不良事件报告系统（FAERS）药品不良反应（Adverse Drug Reaction, ADR）报告。该数据集通过SAS® 9.4软件从季度ASCII格式文件中处理得到，随后以primaryid与caseid为关键字完成排序、合并与标准化操作，并在相关场景下应用了医学术语词典（Medical Dictionary for Regulatory Activities, MedDRA）27.0版。