Difamilast ointment in adult patients with atopic dermatitis: A phase 3 randomized double-blind vehicle-controlled trial

Supplementary material A details the Investigator Global Assessment Score used to assess the primary endpoint. Supplementary material B lists the full exclusion criteria. Supplementary material C details the study investigators and study sites. Supplementary material D presents the disposition of patients throughout the study. Supplementary material E shows the least-square (LS) mean change in verbal rating scale (VRS) for pruritus score from baseline at each time point.

补充材料A详述了用于评估主要终点的研究者整体评估评分（Investigator Global Assessment Score）。补充材料B列出了完整的排除标准。补充材料C详述了本研究的研究人员与研究中心信息。补充材料D呈现了患者在整个研究期间的转归情况。补充材料E展示了各时间点下，瘙痒评分的语言评定量表（verbal rating scale, VRS）得分相较于基线的最小二乘（LS）均数变化。