Distribution of mutational status.
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https://figshare.com/articles/dataset/_Distribution_of_mutational_status_/1542786
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UM GNAQ and GNA11 mutation status varies with tumor location and eye color. The GNAQ Q209P allele is almost uniquely found in UM originating from the central/choroidal area that is exposed to focused visible light. The GNAQ Q209L mutation, on the other hand, is correlated with light eyes (blue/grey).
Distribution of mutational status.
葡萄膜黑色素瘤(UM)的GNAQ与GNA11突变状态会随肿瘤发生部位及虹膜颜色的不同而改变。其中,GNAQ Q209P等位基因几乎仅存在于起源于受聚焦可见光照射的中央脉络膜区域的UM样本中。另一方面,GNAQ Q209L突变则与浅色系虹膜(蓝色/灰色)相关。
突变状态的分布情况。
创建时间:
2015-09-14



