Bacterial skin infection imprints bone marrow eosinophils to promote allergic skin-lung crosstalk

Summary of the experimental setup: This is a dataset of targeted metabolomics of bone marrow- derived eosinophils from WT (C57BL/6J) female mice epicutaneously infected with Staphylococcus aureus or PBS. Bone marrow cells were harvested on day 7 after infection, were plated and differentiated into eosinophils for 14 days. Metabolomics analysis showed a reconfigured metabolic profile of bone marrow eosinophils derived from S.aureus infected mice versus PBS control mice (n=3). Files description: File 'Rawdata.zip' contains the raw data of all 6 samples. File 'Report_Metab02.xlsx' contains the analyzed data report along with the metadata.实验设置概述： 本数据集为经表皮感染金黄色葡萄球菌（Staphylococcus aureus）或磷酸盐缓冲液（PBS）的野生型（WT，C57BL/6J品系）雌性小鼠的骨髓源性嗜酸性粒细胞（bone marrow-derived eosinophils）靶向代谢组学（targeted metabolomics）数据集。于感染后第7天收集骨髓细胞，体外铺板培养并诱导分化为嗜酸性粒细胞，分化周期为14天。代谢组学分析显示，相较于PBS对照组小鼠，金黄色葡萄球菌感染组小鼠来源的骨髓嗜酸性粒细胞代谢谱发生了重塑（n=3）。 文件说明： 文件"Rawdata.zip"包含全部6个样本的原始数据。 文件"Report_Metab02.xlsx"包含已分析的数据报告及配套元数据（metadata）。