Dataset from Administration of a Challenge Dose of Hepatitis B Vaccine in Subjects Who Previously Received Engerix™-B Vaccine.

To evaluate the response to an additional dose (challenge dose) of hepatitis B vaccine, when given to subjects who had received primary vaccination of Engerix™-B vaccine approximately 72-78 months ago. This protocol posting deals with objectives & outcome measures of the challenge phase. The Protocol Posting has been updated in order to comply with the FDA Amendment Act, Sep 2007.

本研究旨在评估在约72-78个月前已完成安在时（Engerix™-B）乙肝疫苗基础免疫的受试者中，接种乙肝疫苗追加激发剂量（challenge dose）后的免疫应答反应。本方案公示涵盖激发接种阶段的研究目标与结局指标。为符合2007年9月颁布的《美国食品药品监督管理局修正案》（FDA Amendment Act）相关要求，本方案公示已完成更新。