Predicted allele combination frequencies of transporter gene polymorphisms.

Major allele combination formed by ABCB1 (1236C>T, 2677G>T and 3435T>C) and ABCB4 1954A>G polymorphisms in DILI patients and controls. The table outlines major allele combinations with a predicted frequency higher than 5% in the control population. The minor allele in the study cohort is marked in underlined bold faced letters.本研究针对药物性肝损伤（Drug-induced liver injury, DILI）患者与对照人群，解析由ABCB1基因的1236C>T、2677G>T及3435T>C多态位点，与ABCB4基因的1954A>G多态位点构成的主要等位基因组合。本表格梳理了对照人群中预测频率高于5%的主要等位基因组合，研究队列中的次要等位基因以带下划线的粗体字体标注。