Association of admission ChE activity with neurocognitive (GCS, MMSE) and functional scores examined both on admission (in) and at discharge (out) in TBI patients (Spearman’s correlation).

It was revealed the positive correlations of ChE activity with neurocognitive scores (GCS, MMSE) and neurofunctional score (QLI, FIM, GOS), but negatively with impairment scores (MRS, RDS, DRS-F).Association of admission ChE activity with neurocognitive (GCS, MMSE) and functional scores examined both on admission (in) and at discharge (out) in TBI patients (Spearman’s correlation).

研究表明，胆碱酯酶（ChE）活性与神经认知评分（格拉斯哥昏迷量表Glasgow Coma Scale, GCS、简易精神状态检查表Mini-Mental State Examination, MMSE）及神经功能评分（生活质量指数Quality of Life Index, QLI、功能独立性评定量表Functional Independence Measure, FIM、格拉斯哥预后量表Glasgow Outcome Scale, GOS）呈正相关，而与损伤评分（改良Rankin量表Modified Rankin Scale, MRS、Rankin残疾量表Rankin Disability Scale, RDS、额叶型痴呆评定量表Dementia Rating Scale-Frontal, DRS-F）呈负相关。本研究针对创伤性脑损伤（Traumatic Brain Injury, TBI）患者，采用斯皮尔曼相关性分析（Spearman correlation），检验了入院时的胆碱酯酶活性与患者分别在入院时（in）及出院时（out）的神经认知评分（GCS、MMSE）及功能评分之间的关联。