Additional file 6: of Interaction between prenatal pesticide exposure and a common polymorphism in the PON1 gene on DNA methylation in genes associated with cardio-metabolic disease risk—an exploratory study

Sig-DMPs overlapping with DMRs (interaction model). For each DMP P values are given for the interaction between pesticide exposure and PON1 genotype (P.Value.int_EXP:PON1), and for the exposure effect PON1 R-allele carrier group (P.Value.EXP_when PON1 QR/RR). The mean beta values in each exposure group are listed. (XLSX 82 kb)

与差异甲基化区域（Differentially Methylated Regions, DMRs）存在重叠的显著差异甲基化位点（Significant Differentially Methylated Positions, Sig-DMPs）采用交互模型进行分析。针对每个差异甲基化位点，本数据集提供了农药暴露与对氧磷酶1（Paraoxonase 1, PON1）基因型的交互作用P值（P.Value.int_EXP:PON1），以及PON1 R等位基因携带者亚组的暴露效应P值（P.Value.EXP_when PON1 QR/RR）。同时列出了各暴露组的平均β值。本数据集文件格式为XLSX，大小82 kb。