Greater prenatal PAH exposure was associated with greater body weight in male and female F1 offspring.

Weights of prenatal PAH and control mice were monitored from PND21 day until PND60. Body weight of PAH and control offspring differed significantly by two way ANOVA (GROUP*LITTER SIZE) on PND 25–27 and PND 52–60 for females and PND 30–60 for males. These included differences among females on PND25 (10.84±0.17 g, n = 19 following PAH vs. 8.87±0.90 g, n = 28 following control exposure), PND27 (10.84±0.17 g, n = 19 following PAH vs. 9.79±0.37 g, n = 28 following control exposure), PND52 (19.36±1.69 g, n = 32 following PAH vs. 17.29±1.79 g, n = 41 following control exposure), and PND 60 (22.79±1.92 g, n = 32 following PAH vs. 19.55±2.05 g, n = 41 following control exposure, p

本研究对产前暴露于多环芳烃（Polycyclic Aromatic Hydrocarbons, PAH）的小鼠与对照组小鼠的体重进行了监测，监测周期为出生后第21天（Postnatal Day, PND21）至出生后第60天（PND60）。经双因素方差分析（GROUP*LITTER SIZE，即组别×窝仔数）统计，雌性子代小鼠在PND25-27、PND52-60阶段，雄性子代小鼠在PND30-60阶段，PAH暴露组与对照组的体重均存在显著差异。其中雌性小鼠的体重差异具体如下：PND25时，PAH暴露组为10.84±0.17 g（n=19），对照组为8.87±0.90 g（n=28）；PND27时，PAH暴露组为10.84±0.17 g（n=19），对照组为9.79±0.37 g（n=28）；PND52时，PAH暴露组为19.36±1.69 g（n=32），对照组为17.29±1.79 g（n=41）；PND60时，PAH暴露组为22.79±1.92 g（n=32），对照组为19.55±2.05 g（n=41），p