Increased levels of extracellular microvesicular (EV) let-7g-5p_delta1 correlates with response to MAPK inhibitors in 25 patients with metastatic cutaneous malignant melanoma treated with MAPK inhibitors.

Increased levels of extracellular microvesicular (EV) let-7g-5p_delta1 correlates with response to MAPK inhibitors in 25 patients with metastatic cutaneous malignant melanoma treated with MAPK inhibitors.在25例接受丝裂原活化蛋白激酶（MAPK）抑制剂治疗的转移性皮肤恶性黑色素瘤患者中，细胞外微囊泡（Extracellular Vesicle，EV）中的let-7g-5pΔ1水平升高与MAPK抑制剂的治疗响应相关。