Extensive divergence of transcription factor binding in Drosophila embryos with highly conserved gene expression (part 1)

We sequenced mRNA from blastoderm embryos of Drosophila melanogaster, Drosophila yakuba, Drosophila pseudoobscura and Drosophila virilis. Two samples contain pooled mRNA from several species, and the remaining 24 samples contain mRNA from a single species. Methods: Retinal mRNA profiles of Blastoderm embryos Overall design: Comparison of the evolution of gene expression and regulatory TF binding in early Drosophila embryos.

我们对黑腹果蝇（Drosophila melanogaster）、雅库巴果蝇（Drosophila yakuba）、拟暗果蝇（Drosophila pseudoobscura）及维氏果蝇（Drosophila virilis）的囊胚层胚胎mRNA进行了测序。其中2份样本为多物种混合mRNA，剩余24份样本均来自单一物种。
实验方法：囊胚层胚胎的视网膜mRNA表达谱
实验设计：比较果蝇早期胚胎中基因表达与调控性转录因子（Transcription Factor）结合的演化模式。