Novel DNA methylation targets in oral rinse samples predict survival of patients with oral squamous cell carcinoma

Epigenome-wide association study (EWAS) of oral rinse samples from a cohort of 82 oral squamous cell carcinoma (OSCC) patients. The Illumina Infinium HumanMethylation450 Beadchip was used to obtain DNA methylation profiles across approximately 450,000 CpGs in oral rinse samples. Bisulphite lsconverted DNA from the 82 oral rinse samples were hybridized to the Illumina Infinium HumanMethylation450 Beadchip

本数据集源自一项针对82例口腔鳞状细胞癌（oral squamous cell carcinoma, OSCC）患者队列的漱口液样本的全表观基因组关联研究（Epigenome-wide association study, EWAS）。研究采用Illumina Infinium HumanMethylation450 BeadChip芯片，对漱口液样本中约45万个CpG位点的DNA甲基化谱进行检测。本研究将82份漱口液样本的亚硫酸氢盐转化DNA与Illumina Infinium HumanMethylation450 BeadChip芯片进行杂交。