Palladium-Catalyzed Alkynylation of Secondary α-Bromo Carbonyl Compounds via Stille Coupling

A catalytic intermolecular cross-coupling reaction that couples secondary α-bromo carbonyl compounds with alkynylstannanes to form secondary alkynyl carbonyl compounds via palladium catalysis employing the XPhos ligand is described.本数据集报道了一种催化分子间交叉偶联反应，该反应以钯催化体系结合XPhos配体，使二级α-溴代羰基化合物与炔基锡烷发生偶联，进而生成二级炔基羰基化合物。