Supplementary Table 1 from A Framework to Select Clinically Relevant Cancer Cell Lines for Investigation by Establishing Their Molecular Similarity with Primary Human Cancers

XLS file - 14K, The bladder cell line panel (BLA-36) and its alignment to clinical phenotypes of human tumors using the SRCCM algorithm. For each cell line, its ATCC name is provided, if applicable. Tumor origin indicates the phenotype of the tumor used to derive the cell line, and is provided where known. Cell lines are aligned to the following phenotypes: tissue of origin (bladder, breast, cervix, colorectum, kidney, lung adenocarcinoma, lung squamous cell carcinoma, ovary, prostate, thyroid); stage, muscle-invasive (T2-T4) vs non-muscle invasive (Ta-T1); grade, high (G3-G4) vs. low (G1-G2), DSS, long- vs. short-term survivors, as defined in Materials and Methods. Gene expression profiles for the BLA-36 cell lines are available from the Gene Expression Omnibus (7) Accession #GSE5845, Ref #8. Abbreviations: ATCC, American Type Culture Collection (9); SRCCM, Spearman's rank correlation classification method; DSS, disease specific survival.

XLS格式文件（大小14KB）：包含膀胱细胞系面板（bladder cell line panel, BLA-36），以及通过斯皮尔曼等级相关分类法（Spearman's rank correlation classification method, SRCCM）实现的该细胞系面板与人类肿瘤临床表型的匹配关联数据。针对每一株细胞系，若适用则提供其美国典型培养物保藏中心（American Type Culture Collection, ATCC）编号。肿瘤来源信息用于说明构建该细胞系的原始肿瘤表型，已知相关信息时会一并提供。本数据集所匹配的表型包括：组织来源（膀胱、乳腺、宫颈、结直肠、肾脏、肺腺癌、肺鳞癌、卵巢、前列腺、甲状腺）；肿瘤分期（肌层浸润性[T2-T4期]与非肌层浸润性[Ta-T1期]）；肿瘤分级（高分级[G3-G4级]与低分级[G1-G2级]）；疾病特异性生存期（disease specific survival, DSS）：即按照材料与方法中定义的长期存活者与短期存活者分组。BLA-36细胞系的基因表达谱可从基因表达综合数据库（Gene Expression Omnibus，参考文献7）获取，登录号为GSE5845，对应参考文献8。缩写说明：ATCC：美国典型培养物保藏中心（参考文献9）；SRCCM：斯皮尔曼等级相关分类法；DSS：疾病特异性生存期。