Mutation load in mitochondria-encoded genes of the respiratory complex I, III, IV and V.

aMITOMAP database (http://www.mitomap.org/MITOMAP). bOnly nonsynonymous coding mtDNA mutations were considered.a. MITOMAP数据库（http://www.mitomap.org/MITOMAP）。 b. 仅考虑非同义编码线粒体DNA（mitochondrial DNA，mtDNA）突变。