AF2 models for "Co-translational assembly promotes functional diversification of paralogous proteins" by Mallik, et al.

AF2 models used for analyses presented in "Co-translational assembly promotes functional diversification of paralogous proteins" by Saurav Mallik, Angel F. Cisneros, Christian R. Landry, and Emmanuel D. Levy. These models were used to analyze the structural divergence of 3703 Obligatory Homomer, 697 Mixed, and 181 Obligatory Heteromer pairs. Folders are separated into different categories:- Models of homomers (from Schweke et al., 2024. Cell): . AF2_HM_full_models: Full structures of homodimeric models. . AF2_HM_nodiso3: Core structures of homomeric models, trimmed using scripts from Schweke et al. (2023). - Models of heteromers (generated in this work): . AF2_HET_full_models: Full structures of heterodimeric models. . AF2_HET_nodiso3: Core structures of heteromeric models, trimmed using a modified version of the code from Schweke et al. (2023) to work with heterodimers.本数据集所用的AlphaFold2（AF2）模型，对应Saurav Mallik、Angel F. Cisneros、Christian R. Landry及Emmanuel D. Levy发表于论文《共翻译组装促进旁系同源蛋白的功能多样化》（"Co-translational assembly promotes functional diversification of paralogous proteins"）中的分析工作。 这些模型被用于分析3703对强制同源多聚体（Obligatory Homomer）、697对混合型（Mixed）以及181对强制异源多聚体（Obligatory Heteromer）的结构差异。 数据集文件夹按类别划分如下： —— 同源多聚体模型（源自Schweke等人2024年发表于《细胞》（Cell）的研究）： · AF2_HM_full_models：同源二聚体模型的完整结构。 · AF2_HM_nodiso3：同源多聚体模型的核心结构，采用Schweke等人2023年的脚本进行了截断处理。 —— 异源多聚体模型（本研究构建）： · AF2_HET_full_models：异源二聚体模型的完整结构。 · AF2_HET_nodiso3：异源多聚体模型的核心结构，使用经修改适配异源二聚体的Schweke等人2023年代码版本进行了截断处理。