SH1038744.10FU

UNITE provides a unified way for delimiting, identifying, communicating, and working with DNA-based Species Hypotheses (SH). All fungal ITS sequences in the international nucleotide sequence databases are clustered to approximately the species level by applying a set of dynamic distance values (<0.5 - 3.0%). All species hypotheses are given a unique, stable name in the form of a DOI, and their taxonomic and ecological annotations are verified through distributed, web-based third-party annotation efforts. SHs are connected to a taxon name and its classification as far as possible (phylum, class, order, etc.) by taking into account identifications for all sequences in the SH. An automatically or manually designated sequence is chosen to represent each such SH. These sequences are released (https://unite.ut.ee/repository.php) for use by the scientific community in, for example, local sequence similarity searches and next-generation sequencing analysis pipelines. The system and the data are updated automatically as the number of public fungal ITS sequences grows.

UNITE数据库为界定、识别、传播及处理基于DNA的物种假说（Species Hypotheses，SH）提供了统一的规范化路径。当前国际核苷酸序列数据库中的所有真菌内转录间隔区（Internal Transcribed Spacer，ITS）序列，均通过应用一组动态距离阈值（0.5%~3.0%）聚类至近似物种级别的分类单元。所有物种假说均被赋予唯一且稳定的数字对象标识符（Digital Object Identifier，DOI）格式的专属名称，其分类学与生态学注释信息通过分布式的网络第三方注释工作完成核验。通过整合各物种假说内所有序列的鉴定信息，系统将尽可能将每个物种假说匹配至对应的分类单元名称及其所属的分类层级（如门、纲、目等）。针对每个物种假说，将选取一条经自动或人工指定的序列作为其代表序列。上述代表序列已通过官方发布渠道（https://unite.ut.ee/repository.php）对外公开，供科研共同体开展本地序列相似性搜索、新一代测序分析流程等相关研究工作使用。随着公共真菌ITS序列数据量的持续增长，该系统及其配套数据将自动完成更新。