iPSC-ITGA6 cell function

Induced pluripotent stem cell-derived TM cells (iPSC-TM) can efficiently restore aqueous humor outflow and maintain intraocular pressure homeostasis. Here, we conducted a multi-modal RNA sequencing analysis to characterize the molecular mechanisms underlying TM regeneration.

诱导多能干细胞来源的TM细胞（Induced pluripotent stem cell-derived TM cells，iPSC-TM）可高效恢复房水流出功能并维持眼压稳态。本研究通过多模态RNA测序分析，阐明了小梁网再生的分子机制。