C. difficile and the host fecal microbiota in domestic animals

Carriage of Clostridioides difficile in domestic animals has been linked with community-acquired C. difficile infection in humans. The goal of this study was to determine the prevalence of C. difficile in different domestic animals and associations between C. difficile presence and the host fecal microbiota. This BioProject contains community sequencing data from amplicon sequencing of the V4 region of the 16S rRNA gene of fecal samples from 197 animals (105 Canine, 70 Equine, 15 Feline, 5 Ovine, 1 Alpaca, and 1 Avian) collected at the North Carolina State University Veterinary Hospital. Host metadata and the results of laboratory assays for C. difficile presence, toxin profiling, and strain typing are included.家养动物携带艰难梭菌（Clostridioides difficile），已被证实与人类社区获得性艰难梭菌感染存在关联。本研究旨在明确不同家养动物中艰难梭菌的携带率，以及艰难梭菌定植与宿主粪便微生物群之间的关联。本BioProject包含北卡罗来纳州立大学兽医医院采集的197份动物粪便样本的16S rRNA基因V4区扩增子测序群落测序数据，涉及的动物包括105只犬、70匹马、15只猫、5只绵羊、1只羊驼以及1只禽类。数据集同时包含宿主元数据，以及艰难梭菌定植检测、毒素谱分析和菌株分型的实验室检测结果。