Per allele hazard ratios (HR) and 95% confidence intervals (CI) of previously published breast cancer loci among <i>BRCA2</i> mutation carriers from previous reports and from the iCOGS array, ordered by statistical significance of the region.

1Reporting status of the SNP is either previously reported or novel to this report. 2p-value was calculated based on the 1-degree of freedom score test statistic. 3rs311499 could not be designed onto the iCOGS array. A surrogate (r2 = 1.0), rs311498, was included, however, and reported here. 4Stronger associations were originally reported for the SNP, assuming a dominant or recessive model of the ‘risk allele’.1. 单核苷酸多态性（Single Nucleotide Polymorphism, SNP）的报告状态可分为两类：既往已报道或为本报告首次报道。 2. P值基于自由度为1的得分检验统计量计算所得。 3. rs311499无法在iCOGS array上进行探针设计，故纳入连锁不平衡系数r²=1.0的替代位点rs311498，并于本报告中予以报道。 4. 早期针对该SNP的研究中，若假设“风险等位基因”采用显性或隐性遗传模型，则可报告出更强的关联信号。