Contingency table analysis odds ratios of SNPs previously associated with WNV infection, symptomatic infection, or disease progression.

Odds ratios (ORs) are reported for the minor allele.aThree disease models were used and include WNV symptomatic infection vs. asymptomatic infection (symptomatic infection), WNE/P vs. WNF/M combined with asymptomatic infection (WNE/P), and WNV infection vs. WNV-negative (WNV Infection).bWNV-negative controls (WNV-Neg). For OAS1 and OASL, the Lim et al. WNV-negative samples were used as a control group [11]. For CCR5, the Glass et al. WNV sero-negative cohort was used as a control group [13].cWest Nile encephalitis/paralysis (WNE/P).dWNV-positive cases (WNV-Pos) consisted of WNV symptomatic and asymptomatic WNV-positive cases.*p**p***p****pP-values were corrected for multiple tests using the Bonferroni Correction.针对次要等位基因报告了比值比（Odds Ratios, OR）。a. 共设置3种疾病模型：①西尼罗河病毒（West Nile Virus, WNV）有症状感染与无症状感染对比（下称有症状感染组）；②西尼罗河脑炎/瘫痪（West Nile Encephalitis/Paralysis, WNE/P）与联合无症状感染的西尼罗河热/脑膜炎（WNF/M）对比（下称WNE/P组）；③西尼罗河病毒感染与西尼罗河病毒阴性样本对比（下称西尼罗河病毒感染组）。b. 西尼罗河病毒阴性对照（WNV-Neg）：针对寡腺苷酸合成酶1（OAS1）和寡腺苷酸合成酶样蛋白（OASL），采用Lim等人的西尼罗河病毒阴性样本作为对照队列[11]；针对C-C趋化因子受体5（CCR5），采用Glass等人的西尼罗河病毒血清阴性队列作为对照[13]。c. 西尼罗河脑炎/瘫痪（WNE/P）。d. 西尼罗河病毒阳性病例（WNV-Pos）包含有症状和无症状的西尼罗河病毒阳性感染者。*p**p***p****p P值通过邦费罗尼校正（Bonferroni Correction）完成多重检验校正。