Synthesis, characterization and antibacterial activity of novel poly(silyl ether)s based on palm and soy oils

Abstract In this research, palm oil and soy oil were used as a natural polyol to prepare novel poly(silyl ether)s. Palm oil and soy oil were first converted to monoglyceride by one step via alcoholysis process in the presence of 0.1% CaO as a catalyst. The monoglycerides were characterized by Fourier transform infrared spectrometer (FT-IR), nuclear magnetic resonance (NMR) and iodine test. The novel poly(silyl ether)s were prepared via polycondensation reaction between dimethyldichlorosilane with monoglycerides based on palm and soy oils, respectively. FT-IR, NMR and silicone-29 (29Si NMR) were used to confirm and determine the presence of silicone in the synthesized polymers. Thermal behavior was studied by thermogravimetric analysis (TGA) and differential scanning calorimetry (DSC). Antibacterial activity of the polymers was screened against three different strains of bacteria, namely Escherichia coli E266, Staphylococcus aureus S276 and Salmonella choleeraesuis 10708.

摘要
本研究以棕榈油与大豆油作为天然多元醇，制备新型聚硅醚（poly(silyl ether)s）。首先通过醇解工艺，以0.1%的氧化钙（CaO）作为催化剂，采用一步法将棕榈油与大豆油转化为单甘油酯。采用傅里叶变换红外光谱仪（Fourier transform infrared spectrometer, FT-IR）、核磁共振波谱仪（nuclear magnetic resonance, NMR）以及碘值试验对所得单甘油酯进行表征。分别以棕榈油基单甘油酯与大豆油基单甘油酯为原料，与二甲基二氯硅烷通过缩聚反应制备得到上述新型聚硅醚。采用FT-IR、NMR以及硅-29核磁共振波谱（29Si NMR）对所合成聚合物中的硅组分进行确认与定性分析。采用热重分析（thermogravimetric analysis, TGA）与差示扫描量热法（differential scanning calorimetry, DSC）对聚合物的热行为展开研究。针对3种不同的细菌菌株，即大肠埃希菌（Escherichia coli）E266、金黄色葡萄球菌（Staphylococcus aureus）S276以及猪霍乱沙门菌（Salmonella choleeraesuis）10708，对该聚合物的抗菌活性进行了筛选测试。