ATN 025 Concomitant Medications: Blood Product Transfusions [CRF 4] Dataset in Hepatitis B Vaccination in Youth at Adolescent Trials Network Sites: Effectiveness of Two Strategies and Evaluation of Tools to be Used in Future HIV Prevention Trials

Data from Concomitant Medications: Blood Product Transfusions [CRF 4]
Study Description
A randomized, single-blinded trial evaluating two licensed vaccine products, Recombivax and Twinrix, given in a two-dose schedule to youth at risk for HIV and hepatitis B infection. Primary objectives were to determine immunogenicity of the products in the study population and to determine safety and tolerability of the vaccines given in the two regimens.
HIV and hepatitis B negative youth aged 12 to 17

合并用药数据：血液制品输注[病例报告表4（CRF 4）]
研究概况
本研究为一项随机单盲临床试验，针对HIV与乙型肝炎感染高风险青少年群体，采用两剂次接种方案，评估两款已获批上市的疫苗产品——重组乙型肝炎疫苗（Recombivax）与甲乙肝联合疫苗（Twinrix）——的临床应用效果。本试验的主要研究目标为：明确两款疫苗在受试人群中的免疫原性，以及两种接种方案下疫苗的安全性与耐受性。
受试人群为HIV与乙型肝炎病毒检测呈阴性、年龄介于12至17岁的青少年。