Massively Parallel Domain Insertion Profiling in Ion Channels

Here, we use massively parallel insertional mutagenesis to determine compatibility of domain recombination variants several ion channels with channel surface expression.本研究采用大规模平行插入诱变（massively parallel insertional mutagenesis）技术，以明确多种离子通道的结构域重组变体与通道表面表达之间的兼容性。