RNA sequencing results of wild type and knockout USP11 in E13.5 or E18.5 of cortex based on IlluminaNovaSeq 6000 platform

We found that USP11 expression perturbed neurogenesis. Overall design: Gene expression profiles of knockout USP11 mice in E13.5 and E18.5 cortex were generated by Illumna RNA sequencing and compared to profiles derived from wild type cortex.

我们发现USP11的表达可干扰神经发生。实验整体设计：通过Illumina RNA测序获取胚胎发育第13.5天（E13.5）与第18.5天（E18.5）的USP11基因敲除小鼠大脑皮层的基因表达谱，并将其与野生型小鼠大脑皮层的基因表达谱进行对比分析。