Two distinct epithelial-to-mesenchymal transition programs control invasion and inflammation in segregated tumor cell populations. Two distinct epithelial-to-mesenchymal transition programs control invasion and inflammation in segregated tumor cell populations

The goal of this study is to analyze mRNA transcriptional changes associated with partial and full EMTs undergone by kidney epithelial dog MDCK cells upon treatment with TGFb. Overall design: We performed mRNA-seq on 24 samples from two MDCK sublines: MDCK-II and MDCK-NBL2

本研究旨在分析经转化生长因子β（Transforming Growth Factor β, TGFβ）处理后，Madin-Darby犬肾上皮细胞（Madin-Darby Canine Kidney, MDCK）发生部分与完全上皮间质转化（Epithelial-Mesenchymal Transition, EMT）相关的mRNA转录变化。实验整体设计：本研究对来自两个MDCK细胞亚株（MDCK-II与MDCK-NBL2）的24份样本开展了mRNA测序（mRNA-seq）。