Impact of the estimated glomerular filtration rate on long-term mortality in patients with hypertensive crisis visiting the emergency department

Renal impairment is common in patients with hypertensive crisis who visit the ED. A strong independent association was observed between decreased eGFR and all-cause mortality in these patients. eGFR provides useful prognostic information and permits the early identification of patients with hypertensive crisis with an increased mortality risk. Intensive treatment and follow-up strategies are needed for patients with a decreased eGFR who visit the ED.

因高血压急症（hypertensive crisis）就诊于急诊室（Emergency Department，ED）的患者中，肾功能损害（renal impairment）较为常见。研究观察到，此类患者的估算肾小球滤过率（estimated glomerular filtration rate，eGFR）降低与全因死亡率（all-cause mortality）之间存在显著的独立关联。eGFR可提供具有临床价值的预后信息，能够早期识别出死亡风险升高的高血压急症患者。针对急诊就诊的eGFR降低患者，需实施强化治疗与随访策略。