Participant Follow-up Demographics/Neuropsychological Assessment in Adolescent Master Protocol, PH200

Participant Follow-up Demographics/Neuropsychological Assessment (July 2024). Data updated in 2024 in DASH to include the follow-up time points through the final participant visit in 2020.
Study Description
The PHACS AMP study is designed to define the impact of HIV infection and antiretroviral therapy on pre-adolescents and adolescents with perinatal HIV infection. Domains investigated include growth and sexual maturation; metabolic risk factors for cardiovascular disease; cardiac function; bone health; neurologic, neurodevelopment, language, hearing, and behavioral function; and adolescent gynecology and HPV infection. Biospecimens are available. AMP includes 451 perinatally HIV-infected (PHIV) youth and 227 perinatally HIV-exposed uninfected (PHEU) youth, age 6 to 17 years at study entry. [587 caregivers also enrolled to provide information on their children.]

受试者随访人口统计学/神经心理学评估（2024年7月）。该数据集于2024年在DASH系统中完成更新，涵盖了直至2020年最后一例受试者随访的全部随访时间点数据。
研究概况
PHACS AMP研究旨在明确HIV感染与抗反转录病毒治疗对围生期HIV感染青春期前及青少年群体的影响。本次研究覆盖的领域包括生长发育与性成熟、心血管疾病代谢危险因素、心功能、骨骼健康、神经及神经发育、语言、听力与行为功能，以及青少年妇科与HPV感染情况。该研究可提供生物样本。AMP研究共纳入451名围生期HIV感染青少年（perinatally HIV-infected, PHIV）以及227名围生期HIV暴露未感染青少年（perinatally HIV-exposed uninfected, PHEU），入组时年龄为6至17岁。[另有587名照料者入组，为研究提供其子女的相关信息。]