Crystal Structure of C151S+H178N mutant of Glyceraldehyde-3-phosphate dehydrogenase 1 (GAPDH1) from Staphylococcus aureus MRSA252 complexed with NAD at 2.2 angstrom resolution

Crystal Structure of C151S+H178N mutant of Glyceraldehyde-3-phosphate dehydrogenase 1 (GAPDH1) from Staphylococcus aureus MRSA252 complexed with NAD at 2.2 angstrom resolution Descriptor: Glyceraldehyde-3-phosphate dehydrogenase 1, NICOTINAMIDE-ADENINE-DINUCLEOTIDE Authors: Mukherjee, S, Dutta, D, Saha, B, Das, A.K. Deposit date: 2009-11-22 Release date: 2010-08-18 Last modified: 2023-11-01 Method: X-RAY DIFFRACTION (2.2 Å) Cite: Crystal structure of glyceraldehyde-3-phosphate dehydrogenase 1 from methicillin-resistant Staphylococcus aureus MRSA252 provides novel insights into substrate binding and catalytic mechanism. J.Mol.Biol., 401, 2010

分辨率为2.2埃的耐甲氧西林金黄色葡萄球菌MRSA252株C151S+H178N突变型甘油醛-3-磷酸脱氢酶1（Glyceraldehyde-3-phosphate dehydrogenase 1, GAPDH1）与烟酰胺腺嘌呤二核苷酸（NAD, NICOTINAMIDE-ADENINE-DINUCLEOTIDE）复合物的晶体结构。描述符：甘油醛-3-磷酸脱氢酶1、烟酰胺腺嘌呤二核苷酸。作者：穆克吉（Mukherjee, S）、杜塔（Dutta, D）、萨哈（Saha, B）、达斯（Das, A.K.）。提交日期：2009-11-22；发布日期：2010-08-18；最后修改日期：2023-11-01。实验方法：X射线衍射（2.2 Å）。引用文献：《耐甲氧西林金黄色葡萄球菌MRSA252株甘油醛-3-磷酸脱氢酶1的晶体结构为底物结合与催化机制提供新见解》，J.Mol.Biol., 401, 2010。