Summary of Sterile Protection in Five Pk4 DNA/Pox Vaccine Studies.

Summary of five published vaccine studies in rhesus monkeys using the Pk4 DNA/Pox vaccine and challenge with 100 Pk sporozoites IV. Trial a is the present experiment. Trial b is from Rogers (18). Trials c and e are from experiment 3 in Weiss (19), Trial d is from experiments 1 and 2 in Weiss (19). N gives the number of animals receiving the Pk4 DNA/Pox vaccine, and Sterile gives the number of animals which did not develop parasites in the blood. Longer regimens give higher proportion of sterilely protected animals.本数据集汇总了5项已发表的恒河猴疫苗研究，所有研究均采用Pk4 DNA/痘病毒（Pox）疫苗，并通过静脉注射（IV）方式攻毒100个Pk子孢子。试验a为本项实验；试验b源自Rogers的研究(18)；试验c与e均取自Weiss的研究(19)中的实验3，试验d则取自该研究中的实验1与实验2。其中，N代表接受Pk4 DNA/痘病毒疫苗免疫的动物数量，Sterile（无虫血症保护）代表血液中未检出寄生虫的动物数量。免疫方案持续时间越长，获得无虫血症保护的动物占比越高。