Cytotoxicity and therapeutic index of peptides.

aGM, geometric mean of the MICs of the peptides against S. pseudintermedius strains.
bIC50 (Inhibitory Concentration 50), peptide concentration that inhibits 50% of macrophage cell line (J774A.1) or human keratinocyte (HaCat).
cTI (Therapeutic index), the ratio of the IC50 over the geometric mean MIC value.
ND: not determined.
Cytotoxicity and therapeutic index of peptides.

aGM：多肽对中间葡萄球菌（Staphylococcus pseudintermedius，S. pseudintermedius）菌株的最小抑菌浓度（Minimum Inhibitory Concentration，MIC）的几何平均值。
bIC50：即半数抑制浓度（Inhibitory Concentration 50，IC50），指可抑制50%巨噬细胞系（J774A.1）或人角质形成细胞（HaCat）生长的多肽浓度。
cTI：即治疗指数（Therapeutic index，TI），为IC50与MIC几何平均值的比值。
ND：未测定（not determined）。
多肽的细胞毒性与治疗指数。