Data sets and query script used in identifying FAM129B as a putative regulator of Wnt/β-catenin signaling using large-scale siRNA screen integrated with phosphoproteomic and bioinformatic analyses.

Data File 1. Results of a large-scale siRNA screen for Wnt/β-catenin signaling in HT1080 B/R cells. Column a contains the siRNA probe ID. Column b contains the ENTREZ gene ID. Coulnm D shows median percent enhancement or inhibition of BAR reporter relative to control siRNA. All data are normalized to constitutively expressed renilla. P-value calculated using student's T. if, for a given gene, all siRNA shows a twofold change in med(normFFluc) and a -logP

数据文件1：针对HT1080 B/R细胞中Wnt/β-catenin信号通路进行的大规模siRNA筛选结果。列a包含siRNA探针ID。列b包含ENTREZ基因ID。列D展示相对于对照siRNA，BAR报告基因的中位百分比增强或抑制。所有数据均归一化至恒定表达的荧光素酶。采用学生t检验计算P值。对于特定基因，若所有siRNA均显示出中位荧光素酶荧光强度（normFFluc）的倍数变化，以及-LogP值