Sfrp1 is predicted to be a regulator of the M9.

aSNPs = The number of SNPs (from dbSNP128) that overlap probes for each gene that may be giving rise to falsely significant eSNP. Note that the probe representing Sfrp1 does not overlap with a known SNP.bOverlap = The percentage of module 9 genes correlated with Sfrp1 at |r>0.25|.cME r = Pearson correlation between each candidates expression and the module 9 eigengene.dLEO.NB.AtoB = The log2 ratio of the causal model fit over the fit of all other possible models (see Methods). A positive causal score≥1 indicates that the eSNP is predicted to be upstream and causal for the module 9 eigengene.aSNPs：指每个基因的探针所覆盖的、来自dbSNP128数据库的单核苷酸多态性（Single Nucleotide Polymorphism, SNP）数量，这类多态性可能会导致产生假阳性显著的eSNP（表达相关单核苷酸多态性，expression SNP）。需注意，代表Sfrp1基因的探针未与任何已知SNP发生重叠。 bOverlap：指模块9中与Sfrp1基因的相关系数绝对值|r|>0.25的基因所占比例。 cME r：指各候选基因的表达量与模块9特征基因（module eigengene）之间的皮尔逊相关系数。 dLEO.NB.AtoB：指因果模型拟合度相较于所有其他可能模型拟合度的以2为底的对数比值（详见方法部分）。当因果得分≥1且为正时，表明该eSNP被预测为位于模块9特征基因的上游且具有因果调控关联。