Quartet of familiar males – 16p11.2 Del mouse strain – 2 WT + 2 Del/+ - M7

We monitored the individual and social behaviours of each quartet of mice over three days and nights in the Live Mouse Tracker system (LMT, plugin 931; de Chaumont et al. 2019 Nat. Biomed. Engin.). This system tracks individually mice living in a group over several days and nights and extracts automatically the number, total duration and mean duration of more than thirty behavioural events describing the posture of the mouse, the types of social contacts, the dynamic social approach and escapes and complex social groupings (see de Chaumont et al. 2019 Nat. Biomed. Engin.). In this system, the four mice (10-14 weeks of age; 2 WT mice and 2 Del/+ mice) from the same housing cage (housed together from weaning on) were left undisturbed for 71 hours in a large transparent Plexiglas cage (50 x 50 x 40 cm), with fresh bedding, a house (width: 100 mm, depth: 75 mm, height: 40 mm) in red Plexiglas, 6 dental cotton rolls as well as food and water ad libitum. Light/dark cycle and temperature conditions were similar to those of the housing room (12/12h light/dark, lights on at 07:00 AM, 100 lux when the lights were on). Each recording session started between 03:00 and 04:00 PM. At the end of the session, mice were placed back in their home cage and the LMT setup was cleaned with soap water and dried with paper towels. The upload includes the sqlite database from LMT (processed).我们于三昼三夜期间，在活体小鼠追踪系统（Live Mouse Tracker，简称LMT，插件版本931；de Chaumont等，2019，《自然·生物医学工程》）中，对每一组四只小鼠的个体行为与社会行为开展了监测。该系统可对群居饲养的小鼠进行多日连续个体追踪，并自动提取三十余种行为事件的发生频次、总时长与平均时长，涵盖小鼠姿态、社会接触类型、动态社交趋近与逃离行为，以及复杂社交群体互动模式（详见de Chaumont等，2019，《自然·生物医学工程》）。本实验所用的4只10~14周龄小鼠均来自同一饲养笼（自断奶起即群居饲养），其中包含2只野生型（Wild Type，WT）小鼠与2只Del/+杂合小鼠，这些小鼠在规格为50×50×40 cm的大型透明聚甲基丙烯酸甲酯（Plexiglas，俗称有机玻璃）饲养箱中不受干扰地停留71小时，箱内铺有新鲜垫料，设有1个红色聚甲基丙烯酸甲酯材质的栖屋（宽100 mm、深75 mm、高40 mm）、6支牙科棉卷，并配备充足的食物与自由取用的饮用水。实验的光照-黑暗周期与环境温度均与原饲养室保持一致：采用12小时光照/12小时黑暗循环，每日07:00开灯，光照强度为100勒克斯。每次记录时段均于下午15:00~16:00之间启动。记录结束后，将小鼠放回原饲养笼，并用肥皂水清洁LMT实验装置，再以纸巾擦干。本次上传内容包含经预处理的LMT系统sqlite数据库文件。