Acetylcytidine modification of DDX41 and ZNF746 by N-acetyltransferase 10 contributes to chemoresistance of melanoma

We performed RNA-seq to analyse the different expression genes of DTIC-resistant (DR) A375 cells and wild-type control. Overall design: Examination of differentially expressed genes in DR A375 cells compared with wild-type control.我们通过RNA测序（RNA-seq）分析达卡巴嗪耐药（DTIC-resistant, DR）A375细胞与野生型对照细胞的差异表达基因。整体实验设计：检测达卡巴嗪耐药A375细胞相较于野生型对照细胞的差异表达基因。