CUT&RUN of H3K4me1 in mESC

Profiling of H3K4me1 genome wide occupancy in mESC WT, LSD1 KO, and rescued with WT LSD1 (RO) and with mutant LSD1 (AK) to explore the effects of LSD1 on histone methylation.

本数据集针对野生型（WT）、LSD1基因敲除（KO）、回补野生型LSD1（RO组）以及回补突变型LSD1（AK组）的小鼠胚胎干细胞（mESC），开展了组蛋白H3第4位赖氨酸单甲基化（H3K4me1）的全基因组占据谱分析，以探究LSD1对组蛋白甲基化的调控效应。