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Transcriptional landscape of three exhausted CD8 T cell subsets. Transcriptional landscape of three exhausted CD8 T cell subsets

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NIAID Data Ecosystem2026-03-11 收录
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https://www.ncbi.nlm.nih.gov/bioproject/PRJNA631925
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Transcriptional analysis of exhausted CD8 Tcell subsets after eliminating chronic antigen stimulation at the single cell level Overall design: LCMV-specific P14 cells were sorted from mice infected with LCMV-Arm or LCMV-Cl13, as well as mice that received donor P14 TEX or TMEM were transcriptionally profiled

单细胞水平下慢性抗原刺激消除后耗竭性CD8 T细胞亚群(exhausted CD8 T cell)的转录分析 整体实验设计:从感染LCMV-Arm或LCMV-Cl13的小鼠,以及接受供体P14耗竭性T细胞(T cell exhausted, TEX)或P14记忆性T细胞(memory T cell, TMEM)的小鼠中分选得到LCMV特异性P14细胞,并对上述细胞进行转录谱分析
创建时间:
2020-05-12
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