Epigenetic signature of exposure to maternal Trypanosoma cruzi infection in cord blood cells from uninfected newborns. Supplementary data.

<strong>Supplementary Table S1. Gene function and ontogeny.</strong> Supplementary Figure 1. Methylation level of differentially methylated CpG sites. After adjustment over all umbilical cord cell types, 12 CpGs yielded experiment-wide level of significance when combining the effects of all cell types (A-L). Data are presented as box plots of the methylation levels determined as the tensor() function in TCA for Unexposed ad Exposed groups (See text for additional methods). Ten sites were hypomethylated, and two were hypermethylated. Sites in A-I were detected in B cells and sites in J-L in CD4+ T cells.

补充表S1：基因功能与个体发育。
补充图1：差异甲基化CpG位点的甲基化水平。在对所有脐带血细胞类型进行校正后，结合所有细胞类型的效应（A-L组），共12个CpG位点达到实验全域显著性水平。数据以箱线图形式呈现，展示了未暴露组与暴露组通过TCA中的tensor()函数计算得到的甲基化水平（详细方法参见正文）。其中10个位点呈低甲基化状态，2个位点呈高甲基化状态。A-I组的位点在B细胞中被检出，J-L组的位点则在CD4+ T细胞中被检出。