Cerebral perfusion and hemodyamics in Alzheimer mouse models

ArcAb mouse model of AD and wild-type littermates at 6-months and 24-months of age.<br>1) ASL-MRI for perfusion imaging<br>2) MSOT imaging for brain oxygenation <br><br>Ten Wild-type C57/B6 mice at 12 weeks for oxygen-challenged MSOT measurement under normoxia and hyperoxia conditions.<br>3) MSOT imaging for brain oxygenation<br>4) Calcuated Oxygen saturation (SO2) color map in mouse brain under different oxygen supply.<br><br>

ArcAb 阿尔茨海默病（AD）小鼠模型，以及6月龄和24月龄的野生型同窝仔鼠。<br>1) 动脉自旋标记磁共振成像（ASL-MRI）用于灌注成像<br>2) 多光谱光声层析成像（MSOT）用于脑氧合成像<br><br>选取10只12周龄的野生型C57/B6小鼠，在常氧和高氧条件下开展氧挑战实验的MSOT测量。<br>3) 多光谱光声层析成像（MSOT）用于脑氧合成像<br>4) 不同供氧条件下小鼠脑内的计算血氧饱和度（SO2）彩色图谱。