Table_1_Health Conditions and Psychotic Experiences: Cross-Sectional Findings From the American Life Panel.xlsx

Background: People with psychotic disorders have poor health, but studies have shown that people who have a milder and more prevalent form of psychosis (psychotic experiences) are also at risk for health problems. More research is needed to examine a broad range of health conditions to discover new relations with psychotic experiences.
Methods: We analyzed cross-sectional data from the American Life Panel, a nationally representative sample of the United States adult population. Using multivariable logistic regression, we examined the associations between health conditions (categories of conditions, specific conditions, count of conditions) and lifetime psychotic experiences.
Results: Approximately 71% of the weighted sample reported at least one health condition, and around 18% reported a lifetime psychotic experience. Using multivariable logistic regression, we found that several health conditions were associated with psychotic experiences, including pain due to other causes, neck pain, other injury, any gastrointestinal/kidney problem, liver diseases/cirrhosis, any nervous/sensory problem, migraine, nerve problem causing numbness/pain, any other disorder, specifically sleep disorder, chronic fatigue syndrome, and chronic pain. Further, the count of specific health conditions and the count of categories were associated with greater odds of psychotic experiences.
Conclusion: We found that numerous health conditions were associated with psychotic experiences.

研究背景：患有精神病性障碍的人群健康状况普遍较差，但已有研究显示，表现为程度更轻、更为普遍的精神病性症状（psychotic experiences）的个体，同样面临健康问题风险。目前仍需开展更多研究，对广泛的健康状况进行考察，以揭示其与精神病性症状间的潜在新关联。
研究方法：本研究针对取自美国生活面板（American Life Panel）的横断面数据展开分析，该数据集为具有全国代表性的美国成年人群抽样样本。本研究采用多变量逻辑回归（multivariable logistic regression）方法，考察了健康状况（按类别划分的健康状况、具体健康问题、健康问题数量）与终身精神病性症状之间的关联。
研究结果：经加权后的样本中，约71%的个体报告存在至少一种健康问题，约18%的个体报告曾出现终身精神病性症状。通过多变量逻辑回归分析，本研究发现多种健康状况与精神病性症状存在关联，包括其他原因所致疼痛、颈部疼痛、其他损伤、任意胃肠道/肾脏问题、肝脏疾病/肝硬化、任意神经/感觉系统疾病、偏头痛、引发麻木或疼痛的神经病变、其他各类障碍，具体包括睡眠障碍、慢性疲劳综合征以及慢性疼痛。此外，具体健康问题的数量以及健康类别数量均与精神病性症状的发生风险呈正相关。
研究结论：本研究发现，众多健康状况均与精神病性症状存在关联。