Effect of collagen on oral squamous cell carcinoma in lactate environment.

To further investigate how collagenous rise caused by lactate affects CSC properties, we transfected SCC9 squamous cell cancer cell lines using empty vectors and COL1A1 knockdown for RNA-seq.

为深入探究乳酸诱导的胶原表达升高如何影响癌症干细胞（Cancer Stem Cell, CSC）的特性，我们采用空载体与COL1A1基因敲低载体分别转染SCC9鳞状癌细胞系，以开展RNA-seq测序分析。