Chr16-HPP. Shotgun Analysis improvement. JPR HPP Special issue 2013. MCF7 Cell line.

The Chromosome 16 Consortium is integrated in the Human Proteome Project that aims to develop an entire map of the proteins encoded by the human genome following a gene-centric strategy (C-HPP) to make progress in the understanding of human biology in health and disease (B/D-HPP). To do this study four human cell lines were selected, MCF7 epithelial cells, CCD18 colon fibroblasts, Ramos and Jurkat B and T lymphocytes respectively. In particular, this subset includes all the data regarding the MCF7 cell line. 6 laboratories contributed to compile all the reported data.

16号染色体研究联盟（Chromosome 16 Consortium）隶属于人类蛋白质组计划（Human Proteome Project, HPP）。该计划旨在绘制人类基因组编码蛋白质的完整图谱，采用以基因为中心的研究策略（C-HPP），以推进人类健康与疾病状态下生物学机制的认知研究（B/D-HPP，即生物学与疾病人类蛋白质组计划）。为开展本项研究，团队选取了4株人类细胞系，分别为MCF7上皮细胞、CCD18结肠成纤维细胞、Ramos细胞以及Jurkat细胞（依次对应B淋巴细胞与T淋巴细胞）。具体而言，本数据集子集涵盖了与MCF7细胞系相关的全部数据。本次报告的所有数据均由6家实验室协作整理完成。