A computational method for predicting the most likely evolutionary trajectories in the stepwise accumulation of resistance mutations

Supporting information dataset for <em>A computational method for predicting the most likely evolutionary trajectories in the stepwise accumulation of resistance mutations, </em>including Flex ddG binding free energy predictions, epistasis calculations, pathway probabilities, Rosetta files and structural files.本数据集为论文《一种预测耐药突变逐步积累过程中最可能进化轨迹的计算方法》（A computational method for predicting the most likely evolutionary trajectories in the stepwise accumulation of resistance mutations）的配套支撑信息数据集，涵盖柔性ddG（Flex ddG）结合自由能预测结果、上位性（epistasis）计算结果、通路概率数据、罗塞塔（Rosetta）格式文件以及结构文件。